KDM2B Polyclonal Antibody

Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
[Histone-H3]-lysine-36 demethylase 1B, CXXC-type zinc finger protein 2, CXXC2, F box and leucine rich repeat protein 10, F box protein FBL10, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, Fbl10, FBXL10, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein, JHDM1B, JmjC domain-containing histone demethylation protein 1B, Jumonji C domain containing histone demethylase 1B, Jumonji domain-containing EMSY-interactor methyltransferase motif protein, kdm2b, KDM2B, Lysine (K) specific demethylase 2B, Lysine-specific demethylase 2B, PCCX2, Protein containing CXXC domain 2, Protein JEMMA, Protein-containing CXXC domain 2

Immunogen: Synthetic peptide of human KDM2B

Swissprot: Q8NHM5
Gene Accession: NP115979

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.66 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.