KDM4A Polyclonal Antibody

Background:
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
JHDM3A, JmjC domain containing histone demethylation protein 3A, JmjC domain-containing histone demethylation protein 3A, JMJD2, JMJD2A, jumonji C domain containing histone demethylase 3A, Jumonji domain containing 2, Jumonji domain containing 2A, Jumonji domain containing protein 2A, Jumonji domain-containing protein 2A, KDM4A, KDM4A, KIAA0677, Lysine (K) specific demethylase 4A, Lysine-specific demethylase 4A, TDRD14A, Tudor domain containing 14A

Immunogen: Synthetic peptide of human KDM4A

Swissprot: O75164
Gene Accession: NP_055478

Calculated MW: 121 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-54624