KDM4C Polyclonal Antibody

Background:
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
bA146B14.1, GASC 1 protein, GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain containing histone demethylation protein 3C, JmjC domain-containing histone demethylation protein 3C, JMJD2C, Jumonji domain containing 2C, Jumonji domain containing protein 2C, Jumonji domain-containing protein 2C, Kdm4c, KDM4C, Lysine (K) specific demethylase 4C, Lysine demethylase 4C, Lysine-specific demethylase 4C, TDRD14C, Tudor domain containing 14C

Immunogen: Synthetic peptide of human KDM4C

Swissprot: Q9H3R0
Gene Accession: NP_055876

Calculated MW: 120 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-104949