KDM4D polyclonal antibody, anti-human, mouse, rat

Background:
It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,Belongs to the JHDM3 histone demethylase family.,Contains 1 JmjC domain.,Contains 1 JmjN domain.,

Research Area: Epigenetics and nuclear signaling

Synonyms: Lysine-specific demethylase 4D , EC 1.14.11.-, JmjC domain-containing histone demethylation protein 3D, Jumonji domain-containing protein 2D

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year