KDM5A Polyclonal Antibody

Background:
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts witHuman, Mouseany other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
Histone demethylase JARID1A, JARID1A, Jumonji/ARID domain containing protein 1A, Jumonji/ARID domain-containing protein 1A, Kdm5a, KDM5A, Lysine-specific demethylase 5A, RBBP-2, RBBP2, RBP2, Retinoblastoma binding protein 2, Retinoblastoma-binding protein 2

Immunogen: Synthetic peptide of human KDM5A

Swissprot: P29375
Gene Accession: NP_001036068

Calculated MW: 192 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-109001/sc-107998/sc-98358