KDM5C / Jarid1C / SMCX (clone 2E4-E1-G8), anti-human antibody
€295.00
In stock
SKU
AC-ABV12039-100
Catalog Number: AC-ABV12039-100
Size: 100 µg
Host: Human IgG
Applications: WB, IF
Datasheet
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Size: 100 µg
Host: Human IgG
Applications: WB, IF
Datasheet
Request Information
Background:
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2
Other Names:
MRXJ, SMCX, MRXSJ, XE169, MRXSCJ, JARID1C, DXS1272E, Lysine-specific demethylase 5C, Jumonji/ARID domain-containing protein 1C
Primary Accession: P41229
Gene Name: KDM5C (HGNC:11114)
Gene ID: 8242
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2
Other Names:
MRXJ, SMCX, MRXSJ, XE169, MRXSCJ, JARID1C, DXS1272E, Lysine-specific demethylase 5C, Jumonji/ARID domain-containing protein 1C
Primary Accession: P41229
Gene Name: KDM5C (HGNC:11114)
Gene ID: 8242
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