KEAP1 monoclonal, anti-human

KEAP1 monoclonal, anti-human

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In stock
SKU
AC-AM1968b
Catalog Number: AC-AM1968b
Size: 80 µl, 400 µl
Isotype: mouse IgM,k
Clone Name: 297CT6.1.6
Applications: WB
Datasheet

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Background:
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Other Names:
Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1, INRF2, KIAA0132, KLHL19

Target/Specificity:
This KEAP1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 422-449 amino acids from human KEAP1.

Antigen Region:
422-449

Antigen Type: Synthetic Peptide

Gene Name: KEAP1 {ECO:0000303|PubMed:14585973, ECO:0000312|HGNC:HGNC:23177}
Gene ID: 9817
Primary Accession: Q14145
NCBI Accession: NP_036421.2;NP_987096.1
Other Accession: Q684M4; NP_036421.2; NP_987096.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
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