Keratin 17 (clone E3), anti-human, rat, bovine, cat, dog, goat, pig, rabbit

Source:
A BALB/c mouse was immunized with an intermediate filament preparation of rat colon mucosa.

Specifications:
E3 reacts with keratin 17 (45 kDa). The antibody reveals myoepithelial cells, basal cells and proliferating epithelia in some benign epithelial tumorsas well as malignant carcinomas.

Species reactivity:
Positive: cat, cow, dog, goat, human, pig, rabbit, rat.

Applications:
Keratin 17 antibodies serve in various antibody panels used for the differential diagnosis of a number of malignancies (breast cancer, lung cancer, ampullary cancer, intestinal vs. pancreatobiliary cancer).
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: Citrate
Western blot: +

Positive control: T24 cells or skin. Bladder or cervix.

References:
- Balm A.J.M., Eur. Arch. Otorhinolaryngol. 253: 227-233 (1996).
- Kozaki, M et al. J. Vet. Med. Sci.63(1): 1-4 (2001).
- Smedts, F., et. al. Am. J. Pathol. 141(2): 497-511 (1992).
- Smedts, F., et. al. Am. J. Pathol. 140(3): 601-612 (1992).
- Wetzels, RH, et. al. Histopathol. 20: 295-303 (1992).
- Troianovskiĭ, SM, Buill.Eksp. Biol. Med.101(6): (1986).