Keratin (50-60kDa (clone 7H5-B5-B6-G8), anti-human, mouse, rat

Background:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Synonyms: CK5, DDD, DDD1, EBS2, K5, KRT5A

Cellular Location: Intracellular Cytoplasm Cytoskeleton

Immunogen:
Purified recombinant human KRT5 beta protein fragments expressed in E.coli.

Gene Symbol: Keratin(50-60kDa)

Gene ID: 3852

Swiss prot: P13647

Calculated MW: 62kDa

Recommended dilution:
WB 1:2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.