Keratin K26 (K25irs2) polyclonal, anti-human

Quantity: 25 µl

Background:
The protein encoded by this gene is a member of the keratin superfamily. This keratin protein is a type I keratin that is specific for the inner root sheath of the hair follicle. This gene exists in a cluster with other keratin genes on chromosome 17q21.

Synonyms:
KRT26, K26, CK26, KRT25B, K25IRS2

Isotype: Guinea pig Polyclonal (CK M4neu.1)

Immunogen:
Synthetic peptide of human keratin K26 (formerly alsodesignated keratin K25irs2); aa 397-411 (KSK STC YKSKGY RPV), coupled to KLH

Form: Stabilized Serum

Specificity:
Specific for human irs-specific keratin K26. The antiserum stains specifically the cuticle layer of the inner root sheath (irs) of the human hair follicle. Negative on all other epithelia tested.

Reactivity: human

Applications: Suitable for immunohistochemistry on frozen sections, immunoblotting

Working DIlution: 1 : 100 for immunohistochemistry; 1 : 1,000 for Western blotting (ECL)

Storage: 2-8C

References:
- Langbein L et al. (2006) J Invest Dermatol 126: 2377-2386