Keratin-pan polyclonal antibody, anti-human, mouse, rat

Background:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Research Area: Signal transduction

Synonyms: Keratin, type II cytoskeletal 2 epidermal, KRT2, KRT76, KRT3, KRT5, KRT6A, KRT6B, KRT6C, KRT71, KRT72, KRT73, KRT74, KRT75, KRT79, KRT8, KRT84, Keratin, type II cytoskeletal 2 epidermal, Keratin, type II cytoskeletal 2 oral, Keratin, type II cytoskeletal 3, Keratin, type II cytoskeletal 5, Keratin, type II cytoskeletal 6A, Keratin, type II cytoskeletal 6B, Keratin, type II cytoskeletal 6C, Keratin, type II cytoskeletal 71, Keratin, type II cytoskeletal 72, Keratin, type II cytoskeletal 73, Keratin, type II cytoskeletal 74,

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year