KHDRBS2 (clone 3D12C11), anti-human, mouse

Background:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity)

Research Area: Epigenetics and nuclear signaling

Synonyms: SLM1, SLM-1, bA535F17.1

Immunogen: Purified recombinant fragment of human KHDRBS2 (AA: 160-349) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage