KHDRBS2 polyclonal, anti-human
€388.00
In stock
SKU
BS70718
Background:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability
Alternative Name:
Sam68-like mammalian protein 1, SLM-1, hSLM-1, KHDRBS2, SLM1,
Application Dilution: WB: 1:500 - 1:1000, IHC: 1:100 - 1:200
Specificity: KHDRBS2 polyclonal antibody detects endogenous levels of KHDRBS2 protein.
Immunogen:
A synthetic peptide of human KHDRBS2.
MW: ~ 38 kDa
Swis Prot.: Q5VWX1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability
Alternative Name:
Sam68-like mammalian protein 1, SLM-1, hSLM-1, KHDRBS2, SLM1,
Application Dilution: WB: 1:500 - 1:1000, IHC: 1:100 - 1:200
Specificity: KHDRBS2 polyclonal antibody detects endogenous levels of KHDRBS2 protein.
Immunogen:
A synthetic peptide of human KHDRBS2.
MW: ~ 38 kDa
Swis Prot.: Q5VWX1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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