KHDRBS3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70729
Background:
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.
Alternative Name:
SLM-2, Sam68-like phosphotyrosine protein, KHDRBS3, SALP, SLM2
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: KHDRBS3 polyclonal antibody detects endogenous levels of KHDRBS3 protein.
Immunogen:
Recombinant protein of human KHDRBS3.
MW: ~ 39 kDa
Swis Prot.: O75525
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.
Alternative Name:
SLM-2, Sam68-like phosphotyrosine protein, KHDRBS3, SALP, SLM2
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: KHDRBS3 polyclonal antibody detects endogenous levels of KHDRBS3 protein.
Immunogen:
Recombinant protein of human KHDRBS3.
MW: ~ 39 kDa
Swis Prot.: O75525
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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