Ki-67 (clone ), anti-human

Background:
Ki-67 is a nuclear protein that is expressed in proliferating cells and may be required for maintaining cell proliferation. Ki-67 has been used as a marker for cell proliferation of solid tumors and some hematological malignancies. A correlation has been demonstrated between Ki-67 index and the histopathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors.

Alternative Name:
Antigen KI-67, MKI67, Ki67, Ki 67

Application Dilution: WB: 1:1000-1:2000, IHC/ICC/IF: 1:50-1:200, FC: 1:50-1:100

Specificity: This antibody detects endogenous levels of Ki-67 and does not cross-react with related proteins.

Immunogen:
Recombinant antibody.

MW: ~ 359 kDa

Swis Prot.: P46013

Purification & Purity:
Protein A affinity purified

Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.