KIN polyclonal, anti-human, mouse

Quantity: 100 µg

Background:
DNA/RNA-binding protein KIN17, also known as BTCD or KIN17, is a protein that in humans is encoded by the KIN gene. This gene is mapped to 10p14. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.

Description:
Rabbit IgG polyclonal antibody for DNA/RNA-binding protein KIN17 (KIN) detection. Tested with WB, IHC-P in Human, Mouse.

Synonyms:
antigenic determinant of recA protein homolog antibody, Binding to curved DNA antibody, BTCD antibody, DNA/RNA-binding protein KIN17 antibody, HsKin17 protein antibody, KIN antibody, KIN antigenic determinant of recA protein homolog mouse antibody, KIN17 antibody, Kin17 protein antibody, KIN17_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human KIN recombinant protein (Position: K3-K202). Human KIN shares 98% amino acid (aa) sequence identity with mouse KIN.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.