KIN polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
DNA/RNA-binding protein KIN17, also known as BTCD or KIN17 is a protein that in humans is encoded by the KIN gene. This gene is mapped to 10p14. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.

Description:
Rabbit IgG polyclonal antibody for DNA/RNA-binding protein KIN17 (KIN) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
BTCD antibody, KIN17 antibody, Binding to curved DNA antibody, antigenic determinant of recA protein(mouse) homolog antibody, KIN, antigenic determinant of recA protein homolog antibody, ANTIGENIC DETERMINANT OF RECA, MOUSE, HOMOLOG OF antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human KIN(48-64aa ESHQRQLLLASENPQQF), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human KIN(48-64aa ESHQRQLLLASENPQQF), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.