KIR2DL1/3/4/S4 Polyclonal Antibody

Background:
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain.

Research Area: Immunology

Synonyms:
p58, NKAT, GL183, NKAT2, CD158b, NKAT2A, NKAT2B, CD158B2, KIR-K7b, KIR-K7c, KIRCL23, KIR-023GB/NKAT, NKAT1, p58.1, CD158A, KIR221, KIR-K64/ G9P, CD158D, KIR103, KIR103AS/ KKA3, KIR1D, NKAT8, CD158I, KIR412

Immunogen: Recombinant protein of human KIR2DL3/1/4/S4

Swissprot: P43628,P43626,Q99706
Gene Accession: BC032422/ ADQ31987/ NP_002246/

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.