Kir3.4 polyclonal, anti-human, mouse, rat

Background:
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

Alternative Name:
GIRK-4, CIR, IRK-4, KCNJ5, GIRK4, Cardiac ATP sensitive potassium channel, Cardiac inward rectifier, CIR, G protein activated inward rectifier potassium channel 4, G protein-activated inward rectifier potassium channel 4, GIRK 4, GIRK-4, GIRK4, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, Inward rectifier K+ channel KIR3.4, Inward rectifier potassium channel KIR3.4, inwardly rectifying subfamily J member 5, IRK-4, IRK5, KATP 1, KATP-1, KATP1, KCNJ 5, Kcnj5, KIR 3.4, KIR3.4, LQT13, Potassium channel, Potassium channel inwardly rectifying subfamily J member 5, Potassium inwardly rectifying channel J5, Potassium inwardly rectifying channel subfamily J member 5, potassium voltage-gated channel subfamily J member 5,

Application Dilution:
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Kir3.4 polyclonal antibody detects endogenous levels of Kir3.4 protein.

Immunogen:
Synthetic peptide within N-terminal human Kir3.4.

MW: 48 kDa

Swiss-Prot: P48544(Human) P48545(Mouse) P48548(Rat)

Purification & Purity:
Peptide affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.