KIT polyclonal, anti-human, mouse, rat

Background:
c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation.

Synonyms: C-Kit, CD117, PBT, SCFR

Cellular Location: Cell membrane

Immunogen:
A synthetic peptide of human KIT

Gene Symbol: KIT

Gene ID: 3815

Swiss prot: P10721

Calculated MW: 125kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.