KLF17 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60308
Background:
Krüppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and which coregulators they interact with. KLF17 (Krüppel-like factor 17), whose alternative names include ZNF393 (zinc finger protein 393) or zfp393, is a 389 amino acid nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family. Expressed in testis and ovary, KLF17 may function as a germ cell-specific transcription factor involved in oocyte development and spermatid differentiation. Containing three C2H2-type zinc fingers which bind G/C-rich sites, KLF17 activates transcription from CACCC-box elements.
Alternative Name:
Krueppel-like factor 17, Zinc finger protein 393, KLF17, ZNF393
Application Dilution: WB: 1:500~1:1000
Specificity: KLF17 polyclonal antibody detects endogenous levels of KLF17 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human KLF17.
MW: ~ 43 kDa
Swis Prot.: Q5JT82
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Krüppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and which coregulators they interact with. KLF17 (Krüppel-like factor 17), whose alternative names include ZNF393 (zinc finger protein 393) or zfp393, is a 389 amino acid nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family. Expressed in testis and ovary, KLF17 may function as a germ cell-specific transcription factor involved in oocyte development and spermatid differentiation. Containing three C2H2-type zinc fingers which bind G/C-rich sites, KLF17 activates transcription from CACCC-box elements.
Alternative Name:
Krueppel-like factor 17, Zinc finger protein 393, KLF17, ZNF393
Application Dilution: WB: 1:500~1:1000
Specificity: KLF17 polyclonal antibody detects endogenous levels of KLF17 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human KLF17.
MW: ~ 43 kDa
Swis Prot.: Q5JT82
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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