Klf4 (C-term) RB51076 polyclonal, anti-human
€144.00
In stock
SKU
AC-AP21583b
Background:
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity).
Other Names: Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, Klf4, Ezf, Gklf, Zie
Target/Specificity:
This Mouse Klf4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 378-410 amino acids from the C-terminal region of Mouse Klf4.
Dilution: 1:1000
Calculated MW: 51880
Gene Name: Klf4
Gene ID: 16600
Primary Accession: Q60793
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity).
Other Names: Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, Klf4, Ezf, Gklf, Zie
Target/Specificity:
This Mouse Klf4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 378-410 amino acids from the C-terminal region of Mouse Klf4.
Dilution: 1:1000
Calculated MW: 51880
Gene Name: Klf4
Gene ID: 16600
Primary Accession: Q60793
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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