KLF6 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Krueppel-like factor 6 (KLF6) is a protein that in humans is encoded by the KLF6 gene. It is a tumor suppressor gene which is located on 10p15.1. This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.

Description:
Rabbit IgG polyclonal antibody for Krueppel-like factor 6 (KLF6) detection. Tested with WB in Human, Rat.

Synonyms:
B cell derived protein 1 antibody, B cell-derived 1 antibody, B-cell-derived protein 1 antibody, BCD1 antibody, CBA1 antibody, COPEB antibody, Core promoter element-binding protein antibody, CPBP antibody, GBF antibody, GC rich binding factor antibody, GC rich sites binding factor GBF antibody, GC-rich sites-binding factor GBF antibody, Klf6 antibody, KLF6_HUMAN antibody, Krueppel-like factor 6 antibody, Krueppel-like factor 6 isoform C antibody, Kruppel like zinc finger protein Zf9 antibody, PAC1 antibody, Proto-oncogene BCD1 antibody, Protooncogene B cell derived 1 antibody, ST12 antibody, Suppression of tumorigenicity 12 (prostate) antibody, Suppressor of tumorigenicity 12 protein antibody, Transcription factor Zf9 antibody, Zf9 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.E.coli-derived human KLF6 recombinant protein (Position: E38-N205). Human KLF6 shares 92% and 90% amino acid (aa) sequences identity with mouse and rat KLF6, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.