KLF7 polyclonal antibody, anti-human, mouse
€0.00
In stock
SKU
BT-AP04842
Catalog Number: BT-AP04842
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse
Application(s): WB, ELISA
Datasheet
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Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse
Application(s): WB, ELISA
Datasheet
Request Information
Background:
The protein encoded by KLF7 (Kruppel like factor 7)is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of KLF7 is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
Research Area: Neuroscience
Synonyms: KLF7, UKLF, Krueppel-like factor 7, Ubiquitous krueppel-like factor
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
The protein encoded by KLF7 (Kruppel like factor 7)is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of KLF7 is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
Research Area: Neuroscience
Synonyms: KLF7, UKLF, Krueppel-like factor 7, Ubiquitous krueppel-like factor
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
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