KLF7 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.

Research Area: Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
KLF7, KLF7, Krueppel like factor 7, Krueppel-like factor 7, Kruppel like factor 7, Ubiquitous krueppel like factor, Ubiquitous krueppel-like factor, UKLF

Immunogen: Recombinant protein of human KLF7

Swissprot: O75840
Gene Accession: BC012919

Calculated MW: 33 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.