KLHL12 polyclonal (C-term), anti-human, mouse

Background:
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.

Other Names:
Kelch-like protein 12, CUL3-interacting protein 1, DKIR homolog, hDKIR, KLHL12, C3IP1

Target/Specificity:
This KLHL12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human KLHL12.

Antigen Region:
376-404

Antigen Type: Synthetic Peptide

Gene Name: KLHL12
Gene ID: 59349
Primary Accession: Q53G59
NCBI Accession: NP_067646.1
Other Accession: Q6NRH0; Q8R2H4; Q8BZM0; Q5U374; E1B932; NP_067646.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.