KLHL3 N-terminal region polyclonal, anti-human, mouse, rat, rabbit, zebrafish, pig, dog, guinea pig, horse, bovine

Background:
This is a rabbit polyclonal antibody against KLHL3. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein.

Other Names:
Kelch-like protein 3, KLHL3, KIAA1129

Target/Specificity:
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.

Immunogen:
The immunogen for anti-KLHL3 antibody: synthetic peptide directed towards the N terminal of human KLHL3

Gene Name:
KLHL3 {ECO:0000303|PubMed:10843806, ECO:0000312|HGNC:HGNC:6354}
Gene Name:
26249
Swissprot ID: Q9UH77
NCBI Accession:
NP_059111
Primary Accession: Q9UH77
Other Accession: Q9UH77;NP_059111;NM_017415
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.