KLK1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6644
Background:
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression.
Alternative Name:
Kallikrein-1, Kallikrein 1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein, KLK1
Application Dilution: WB: 1:500 - 1:2000
Specificity: KLK1 polyclonal antibody detects endogenous levels of KLK1 protein.
Immunogen:
Recombinant full length Human KLK1.
MW: ~ 28 kDa
Swis Prot.: P06870
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression.
Alternative Name:
Kallikrein-1, Kallikrein 1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein, KLK1
Application Dilution: WB: 1:500 - 1:2000
Specificity: KLK1 polyclonal antibody detects endogenous levels of KLK1 protein.
Immunogen:
Recombinant full length Human KLK1.
MW: ~ 28 kDa
Swis Prot.: P06870
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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