KLK2 (clone 4B1F7), anti-human

KLK2 (clone 4B1F7), anti-human

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In stock
SKU
BT-MCA2413
Catalog Number: BT-MCA2413
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, ICC, FCM
Datasheet
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Background:
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Research Area: Others

Synonyms: hK2, hGK-1, KLK2A2

Immunogen: Purified recombinant fragment of human KLK2 (AA: 25-261) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage
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