KLK2 Polyclonal Antibody

Background:
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
Glandular kallikrein 2, Glandular kallikrein-1, hGK 1, hGK-1, hK2, Kallikrein 2 prostatic, Kallikrein related peptidase 2, kallikrein, glandular, Kallikrein, prostatic, Kallikrein-2, KLK 2, Klk-2, Klk2, KLK2, KLK2A 2, KLK2A2, MGC12201, Tissue kallikrein 2, Tissue kallikrein-2, Ton

Immunogen: Synthetic peptide of human KLK2

Swissprot: P20151
Gene Accession: NP_005542

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20368