KLK2 Polyclonal Antibody

Background:
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
Glandular kallikrein 2, Glandular kallikrein-1, hGK 1, hGK-1, hK2, Kallikrein 2 prostatic, Kallikrein related peptidase 2, kallikrein, glandular, Kallikrein, prostatic, Kallikrein-2, KLK 2, Klk-2, Klk2, KLK2, KLK2A 2, KLK2A2, MGC12201, Tissue kallikrein 2, Tissue kallikrein-2, Ton

Immunogen: Recombinant Human Kallikrein-2 protein

Swissprot: P20151
Gene ID: 3817

Calculated MW: 17,18,24,28 kDa
Observed MW: 28 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: WB 1:2000-1:3000 IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.