KLK4 Polyclonal Antibody

Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
7S nerve growth factor alpha chain, AI2A1, Alpha-NGF, Androgen-regulated message 1, ARM1, EC 3.4.21.-, EMSP 1, EMSP, EMSP1, Enamel Matrix Serine Protease 1, Enamel matrix serine proteinase 1, HK4, Kallikrein 1-related peptidase-like b4, Kallikrein 4 (prostase, enamel matrix, prostate), Kallikrein 4, Kallikrein, Kallikrein L1, Kallikrein like protein 1, Kallikrein related-peptidase 4 (prostase, enamel matrix, prostate), Kallikrein-4, Kallikrein-like protein 1, Kallikrein-related peptidase 4, KLK 4, KLK L1, KLK-L1, KLK4, KLK4, MGC116827, MGC116828, Prostase, Protease Serine 17, PRSS 17, PRSS17, PSTS, Serine protease 17

Immunogen: Recombinant protein of human KLK4

Swissprot: Q9Y5K2
Gene Accession: BC069429

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20373/sc-20622/sc-20371/sc-80146