KLK5 Polyclonal Antibody

Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
HK5, Kallikrein 5, Kallikrein L2, Kallikrein like 2, Kallikrein like protein 2, Kallikrein related peptidase 5, Kallikrein-5, Kallikrein-like protein 2, Kallikrein5, KLK 5, KLK L2, KLK-L2, KLK5, KLK5, KLKL 2, KLKL2, SCTE, Stratum corneum tryptic enzyme, UNQ570/PRO1132

Immunogen: Synthetic peptide of human KLK5

Swissprot: Q9Y337
Gene Accession: NP_036559

Calculated MW: 32 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20623/sc-20375