KLK6 antibody (clone 4A10), anti-human
€435.00
In stock
SKU
AC-AT2641a
Catalog Number: AC-AT2641a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT2641a">Request Information
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Other Names:
Kallikrein-6, 3421-, Neurosin, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme, KLK6, PRSS18, PRSS9
Antigen Type:
Recombinant Protein
Gene Name: KLK6
Gene ID: 5653
NCBI Accession: NP_001012982.1;NP_001012983.1;NP_002765.1
Primary Accession: Q92876
Other Accession: BC015525
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Other Names:
Kallikrein-6, 3421-, Neurosin, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme, KLK6, PRSS18, PRSS9
Antigen Type:
Recombinant Protein
Gene Name: KLK6
Gene ID: 5653
NCBI Accession: NP_001012982.1;NP_001012983.1;NP_002765.1
Primary Accession: Q92876
Other Accession: BC015525
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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