KLK6 Polyclonal Antibody

Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

Research Area: Cancer, Cell Biology, Neuroscience, Signal Transduction

Synonyms:
Kallikrein related peptidase 6, Klk-8, Klk8, Kallikrein-6, KLK 6, MGC9355, mGK 1, mGK1, MSP, PRSS 18, PRSS 9

Immunogen: Recombinant Rat Prostatic glandular kallikrein-6 protein

Swissprot: P36374

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 0.3 mg/mL
Dilution: IHC 1:100-1:300 IF 1:100-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.