KLK6 Polyclonal Antibody

Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

Research Area: Cancer, Neuroscience, Tags & Cell Markers, Signal Transduction, Cell Biology

Synonyms:
Bssp, hK 6, hK6, Kallikrein 6 precursor, Kallikrein related peptidase 6, Kallikrein-6, Kallikrein6, KLK 6, Klk 7, KLK 9, Klk29, Klk6, KLK6, Klk7, KLK9, MGC9355, mGK 1, mGK1, MSP, Neurosin, Protease M, Protease serine 18, Protease serine 9, PRSS 18, PRSS 9, PRSS18, PRSS9, Serine protease 18, Serine protease 9, SP 59, SP59, Tissue kallikrein, TK, Zyme

Immunogen: Recombinant Human Kallikrein-6 protein

Swissprot: Q92876
Gene ID: 5653

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.