KLK7 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7611
Background:
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Alternative Name:
Chymotryptic stratum corneum, hK 7, hK7, hSCCE, Kallikrein 7 (chymotryptic stratum corneum), Kallikrein related peptidase 7, Kallikrein-7, Kallikrein7, KLK 7, Klk7, KLK7_HUMAN, Protease serine 6, PRSS 6, PRSS6, SCCE, Serine protease 6, Signal protein, Stratum corneum chymotryptic enzyme,
Application Dilution: WB: 1:500 - 1:2000
Specificity: KLK7 polyclonal antibody detects endogenous levels of KLK7 protein.
Immunogen:
Recombinant full length Human KLK7.
MW: ~27 kDa
Swis Prot.: P49862
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Alternative Name:
Chymotryptic stratum corneum, hK 7, hK7, hSCCE, Kallikrein 7 (chymotryptic stratum corneum), Kallikrein related peptidase 7, Kallikrein-7, Kallikrein7, KLK 7, Klk7, KLK7_HUMAN, Protease serine 6, PRSS 6, PRSS6, SCCE, Serine protease 6, Signal protein, Stratum corneum chymotryptic enzyme,
Application Dilution: WB: 1:500 - 1:2000
Specificity: KLK7 polyclonal antibody detects endogenous levels of KLK7 protein.
Immunogen:
Recombinant full length Human KLK7.
MW: ~27 kDa
Swis Prot.: P49862
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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