KLK7 Polyclonal Antibody

Background:
This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
Chymotryptic stratum corneum, hK 7, hK7, hSCCE, Kallikrein 7 (chymotryptic stratum corneum), Kallikrein related peptidase 7, Kallikrein-7, Kallikrein7, KLK 7, Klk7, KLK7, Protease serine 6, PRSS 6, PRSS6, SCCE, Serine protease 6, Signal protein, Stratum corneum chymotryptic enzyme

Immunogen: Recombinant protein of human KLK7

Swissprot: P49862
Gene Accession: BC032005

Calculated MW: 28 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-80148/sc-20625/sc-20380