Klotho polyclonal (C-term), anti-human

Background:
May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).

Other Names:
Klotho, 3.2.1.31, Klotho peptide, KL

Target/Specificity:
This Klotho antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 284-315 amino acids from the C-terminal region of human Klotho.

Antigen Type: Synthesized Peptide

Gene Name: KL
Gene ID: 9365
Primary Accession: Q9UEF7
Other Accession: Q8WP17
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.