KLRA3 polyclonal, anti-mouse, rat
€484.00
In stock
SKU
254011
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide –receptive H-2Kb. This antibody may cross-react with other LY49 receptors.
Alternate Names: KLRA3, Killer cell lectin-like receptor subfamily A member 3, Ly49C, Nk2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: AAI32525
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within mouse KLRA3.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide –receptive H-2Kb. This antibody may cross-react with other LY49 receptors.
Alternate Names: KLRA3, Killer cell lectin-like receptor subfamily A member 3, Ly49C, Nk2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: AAI32525
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within mouse KLRA3.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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