KLRB1 Polyclonal Antibody

Background:
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus.

Research Area: Immunology

Synonyms:
C-type lectin domain family 5 member B, CD161, CLEC5B, HNKR-P1a, Killer Cell Lectin like Receptor Subfamily B Member 1, Killer cell lectin-like receptor subfamily B member 1, KLRB1, KLRB1, Natural killer cell surface protein P1A, NKR, NKR P1, NKR-P1A, NKRP1, NKRP1A

Immunogen: Fusion protein of human KLRB1

Swissprot: Q12918
Gene Accession: BC114516

Calculated MW: 25 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.