KLRC3 antibody (clone 3D5), anti-human
€435.00
In stock
SKU
AC-AT2644a
Catalog Number: AC-AT2644a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT2644a">Request Information
Background:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
NKG2-E type II integral membrane protein, NK cell receptor E, NKG2-E-activating NK receptor, KLRC3, NKG2E
Antigen Type:
Recombinant Protein
Gene Name: KLRC3
Gene ID: 3823
NCBI Accession: NP_002252.2;NP_031359.2
Primary Accession: Q07444
Other Accession: NM_002261
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
NKG2-E type II integral membrane protein, NK cell receptor E, NKG2-E-activating NK receptor, KLRC3, NKG2E
Antigen Type:
Recombinant Protein
Gene Name: KLRC3
Gene ID: 3823
NCBI Accession: NP_002252.2;NP_031359.2
Primary Accession: Q07444
Other Accession: NM_002261
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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