CD94 (KLRD1) polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6645
Background:
The KIR/LIR family includes p91A (also designated pp130 or PIR-B, for paired Immuno-globulin-like receptor-B) and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor. CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoprotein. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ αß T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.
Alternative Name:
CD 94, CD94, CD94 antigen, Killer cell lectin like receptor subfamily D member 1, Killer cell lectin-like receptor subfamily D member 1, KLRD 1, KLRD1, KLRD1 protein, KLRD1, KP 43, KP43, Natural killer cells antigen CD94, NK cell receptor,
Application Dilution: WB: 1:500 - 1:2000
Specificity: KLRD1 polyclonal antibody detects endogenous levels of KLRD1 protein.
Immunogen:
Recombinant full length Human KLRD1.
MW: ~ 21 kDa
Swis Prot.: Q13241
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The KIR/LIR family includes p91A (also designated pp130 or PIR-B, for paired Immuno-globulin-like receptor-B) and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor. CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoprotein. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ αß T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.
Alternative Name:
CD 94, CD94, CD94 antigen, Killer cell lectin like receptor subfamily D member 1, Killer cell lectin-like receptor subfamily D member 1, KLRD 1, KLRD1, KLRD1 protein, KLRD1, KP 43, KP43, Natural killer cells antigen CD94, NK cell receptor,
Application Dilution: WB: 1:500 - 1:2000
Specificity: KLRD1 polyclonal antibody detects endogenous levels of KLRD1 protein.
Immunogen:
Recombinant full length Human KLRD1.
MW: ~ 21 kDa
Swis Prot.: Q13241
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review