KMT2D Polyclonal Antibody

Background:
The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
AAD10, ALL1 related gene, ALL1-related protein, ALR, CAGL114, Histone-lysine N-methyltransferase MLL2, KABUK1, Kabuki make up syndrome, Kabuki mental retardation syndrome, KMS, KMT2B, KMT2D, Lysine N methyltransferase 2D, Lysine N-methyltransferase 2B, MLL2, MLL2, MLL4, Myeloid/lymphoid or mixed lineage leukemia 2, Myeloid/lymphoid or mixed-lineage leukemia protein 2, TNRC21, Trinucleotide repeat containing 21

Immunogen: Synthetic peptide of human KMT2D

Swissprot: O14686
Gene Accession: NP_003473

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-68671/sc-68672/sc-292359