KNG1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6646
Background:
In rats, four types of kininogens are produced, two of which are classical high and low molecular weight kininogens and two of which are low molecular weight-like kininogens, designated T-kininogen 1 and T-kininogen 2. T-kininogen 1 and T-kininogen 2 are 430 amino acid secreted rat proteins that each contain three cystatin domains and have nearly identical functions. Existing in plasma, both T-kininogen 1 and T-kininogen 2 are glycoproteins that act as thiol protease inhibitors and also play a role in blood coagulation, specifically by helping to optimally position blood coagulation factors. Additionally, T-kininogen 1 and T-kininogen 2 act as precursors of the active peptide Bradykinin and, as such, effect vascular permeability, hypotension and smooth muscle contraction.
Alternative Name:
BDK, Kininogen 1, KNG1, LMW, Low molecular weight growth promoting factor, Low molecular weight kininogen,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: KNG1 polyclonal antibody detects endogenous levels of KNG1 protein.
Immunogen:
Recombinant full length Human KNG1.
MW: ~ 70 kDa
Swis Prot.: P01042
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
In rats, four types of kininogens are produced, two of which are classical high and low molecular weight kininogens and two of which are low molecular weight-like kininogens, designated T-kininogen 1 and T-kininogen 2. T-kininogen 1 and T-kininogen 2 are 430 amino acid secreted rat proteins that each contain three cystatin domains and have nearly identical functions. Existing in plasma, both T-kininogen 1 and T-kininogen 2 are glycoproteins that act as thiol protease inhibitors and also play a role in blood coagulation, specifically by helping to optimally position blood coagulation factors. Additionally, T-kininogen 1 and T-kininogen 2 act as precursors of the active peptide Bradykinin and, as such, effect vascular permeability, hypotension and smooth muscle contraction.
Alternative Name:
BDK, Kininogen 1, KNG1, LMW, Low molecular weight growth promoting factor, Low molecular weight kininogen,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: KNG1 polyclonal antibody detects endogenous levels of KNG1 protein.
Immunogen:
Recombinant full length Human KNG1.
MW: ~ 70 kDa
Swis Prot.: P01042
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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