KNG1 Polyclonal Antibody

Background:
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
KNG1, BDK, BK, KNG

Immunogen: Recombinant fusion protein of human KNG1 (NP_000884.1).

Swissprot: P01042
Gene ID: 3827

Calculated MW: 43 kDa/47 kDa/71 kDa
Observed MW: 68 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.