KPNA6 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12228b
Background:
Nucleocytoplasmic transport, a signal- andenergy-dependent process, takes place through nuclear porecomplexes embedded in the nuclear envelope. The import of proteinscontaining a nuclear localization signal (NLS) requires the NLSimport receptor, a heterodimer of importin alpha and beta subunitsalso known as karyopherins. Importin alpha binds the NLS-containingcargo in the cytoplasm and importin beta docks the complex at thecytoplasmic side of the nuclear pore complex. In the presence ofnucleoside triphosphates and the small GTP binding protein Ran, thecomplex moves into the nuclear pore complex and the importinsubunits dissociate. Importin alpha enters the nucleoplasm with itspassenger protein and importin beta remains at the pore. Theprotein encoded by this gene is a member of the importin alphafamily.
Other Names:
Importin subunit alpha-7, Karyopherin subunit alpha-6, KPNA6, IPOA7
Gene Name: KPNA6
Gene ID: 23633
Primary Accession: O60684
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Nucleocytoplasmic transport, a signal- andenergy-dependent process, takes place through nuclear porecomplexes embedded in the nuclear envelope. The import of proteinscontaining a nuclear localization signal (NLS) requires the NLSimport receptor, a heterodimer of importin alpha and beta subunitsalso known as karyopherins. Importin alpha binds the NLS-containingcargo in the cytoplasm and importin beta docks the complex at thecytoplasmic side of the nuclear pore complex. In the presence ofnucleoside triphosphates and the small GTP binding protein Ran, thecomplex moves into the nuclear pore complex and the importinsubunits dissociate. Importin alpha enters the nucleoplasm with itspassenger protein and importin beta remains at the pore. Theprotein encoded by this gene is a member of the importin alphafamily.
Other Names:
Importin subunit alpha-7, Karyopherin subunit alpha-6, KPNA6, IPOA7
Gene Name: KPNA6
Gene ID: 23633
Primary Accession: O60684
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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