KRAS antibody (clone 4F3), anti-human
€435.00
In stock
SKU
AC-AT2651a
Catalog Number: AC-AT2651a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT2651a">Request Information
Background:
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Other Names:
GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase KRas, N-terminally processed, KRAS, KRAS2, RASK2
Antigen Type:
Recombinant Protein
Gene Name: KRAS
Gene ID: 3845
NCBI Accession: NP_004976.2;NP_203524.1
Primary Accession: P01116
Other Accession: NM_004985
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Other Names:
GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase KRas, N-terminally processed, KRAS, KRAS2, RASK2
Antigen Type:
Recombinant Protein
Gene Name: KRAS
Gene ID: 3845
NCBI Accession: NP_004976.2;NP_203524.1
Primary Accession: P01116
Other Accession: NM_004985
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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