KRAS antibody (clone S2), anti-human

Background:
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Other Names:
GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase KRas, N-terminally processed, KRAS, KRAS2, RASK2

Antigen Type:
Recombinant Protein

Gene Name: KRAS
Gene ID: 3845
NCBI Accession: NP_004976.2;NP_203524.1
Primary Accession: P01116
Other Accession: BC013572
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .