KRAS polyclonal (C-term), anti-human, mouse, rat

KRAS polyclonal (C-term), anti-human, mouse, rat

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In stock
SKU
AC-AP16356b
Catalog Number: AC-AP16356b
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB32708
Applications: WB, FC, IF
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Background:
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Other Names:
GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase KRas, N-terminally processed, KRAS, KRAS2, RASK2

Target/Specificity:
This KRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the C-terminal region of human KRAS.

Antigen Region:
146-174

Antigen Type: Synthetic Peptide

Gene Name: KRAS
Gene ID: 3845
Primary Accession: P01116
NCBI Accession: NP_004976.2;NP_203524.1
Other Accession: P08644; P32883; NP_203524.1; NP_004976.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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